MOTS-c (10mg) Mitochondrial-Derived Peptide for Metabolic and Cellular Stress Research
MOTS-c (10mg) is a synthetic mitochondrial-derived peptide (MDP) encoded by the 12S rRNA region of mitochondrial DNA. It plays a central role in metabolic regulation, cellular homeostasis, and stress response signaling. This peptide has garnered significant interest in research focused on mitochondrial activity, insulin sensitivity, and age-related metabolic dysfunctions.
Product Overview Each vial contains 10mg of MOTS-c in lyophilized form, synthesized to >99% purity. It is ideal for experimental studies investigating AMPK pathway activation, oxidative stress modulation, and insulin-mimetic mechanisms. Its unique mitochondrial origin distinguishes it from traditional peptides and supports its investigation in metabolic disease models.
Key Research Attributes:
- Mitochondrial Regulation: MOTS-c is encoded within the mitochondrial genome and regulates cellular metabolism by activating AMPK and related energy pathways.
- Insulin Sensitivity Support: Studied for its role in enhancing glucose uptake and mimicking insulin-like effects in cellular models.
- Stress Response Signaling: Research suggests MOTS-c may protect cells under metabolic or oxidative stress, including hypoxia and aging environments.
- Exceptional Purity: Formulated for precise and repeatable results in controlled laboratory settings.
Applications in Scientific Research
- Mitochondrial function and peptide encoding studies
- Metabolic syndrome and insulin resistance models
- AMPK pathway and energy metabolism regulation
- Oxidative stress and anti-aging cellular mechanisms
- Neuroprotective and cytoprotective stress response investigations
Format and Storage Form: Lyophilized powder Purity: >99% Storage: Store at -20°C in a sealed, moisture-free environment Reconstitution: Use sterile bacteriostatic water in a sterile setting
Disclaimer: MOTS-c (10mg) is intended solely for in vitro and laboratory-based research. It is not for human or veterinary use. All handling must follow institutional and legal research guidelines.
Chemical Makeup
Molecular Formula
- MOTS-c: C136H217N43O27
Molecular Weight
- MOTS-c: 2188.5 g/mol
Sequence
- MOTS-c: MRWQEMGYIFYPRKLR
Other Known Titles
- MOTS-c: Mitochondrial Open Reading Frame of the 12S rRNA Type-c
MOTS-c (10mg) is supplied exclusively for scientific research use. Acceptance of our Terms and Conditions is required prior to ordering.
MORE INFORMATION
| Purity Percentage | 99% Purity |
|---|---|
| Volume | 10MG |
| Bought This Week | 40 |
| New | No |
| Sale | No |
MOTS c Peptide: Research Insights and Applications
MOTS c is a mitochondrial derived peptide that has been investigated for its potential roles in metabolic regulation, cellular stress responses, and healthy aging. Research models suggest it may influence glucose and lipid metabolism, exercise performance, immune function, and neuroprotection through pathways such as AMPK activation and mitochondrial signalling. The sources below outline key findings, mechanisms, and experimental applications.
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Metabolic Regulation through MOTS c Reviews MOTS c activation of AMPK, its impact on glucose and lipid handling, and links to mitochondrial function and metabolic balance. Read more
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Anti Obesity Potential of MOTS c in Animal Models Describes studies where MOTS c improved insulin sensitivity and reduced weight gain in high fat diet mice. Read more
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MOTS c Enhances Exercise Capacity and Endurance Reports increased exercise performance and endurance in mice, with proposed links to mitochondrial biogenesis and energy metabolism. Read more
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Longevity and Aging Related Effects of MOTS c Explores anti aging related findings including cellular resilience, stress resistance, and lifespan extension in preclinical models. Read more
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Neuroprotective Functions of MOTS c Peptide Summarises data on reduced neuroinflammation, improved mitochondrial health, and protection in neural tissue models. Read more
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Immune Modulation and Inflammation Control Reviews regulatory effects on cytokine expression and immune pathways in autoimmune and inflammatory research settings. Read more
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Potential Application in Type 2 Diabetes Models Describes improvements in glucose tolerance and insulin signalling associated with MOTS c in metabolic research. Read more
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MOTS c and Cardiovascular Health Examines effects on vascular integrity, endothelial function, and cardiac protection under metabolic stress. Read more
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Mechanistic Studies on MOTS c and Cellular Energy Balance Details molecular pathways through which MOTS c may influence cellular bioenergetics and stress responses. Read more





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