Tesamorelin is a synthetic analog of Growth Hormone-Releasing Hormone (GHRH). It stimulates the pituitary gland to release growth hormone in its natural rhythm. It is the only FDA-approved GHRH peptide, sold as Egrifta SV and Egrifta WR for HIV-related abdominal fat (lipodystrophy). It is also widely used off-label for visceral fat reduction and body composition.
Vial Sizes & Prices (Research Grade)
Research vials usually come in 2 mg, 5 mg, or 10 mg sizes and are mixed with bacteriostatic water before use. Peptidedosingprotocols
| Vial Size | Approx. Price | Cost per mg |
|---|---|---|
| 2 mg | ~$30–$80 | ~$15–$40/mg |
| 5 mg | ~$60–$130 | ~$12–$26/mg |
| 10 mg | ~$60–$150 | ~$6–$15/mg |
The cheapest research-grade option runs from $5.13/mg post-coupon, but only 4 of 6 vendors publish a COA verifying the correct 5,196 Da molecular weight. Thepeptidecatalog
Monthly Cost by Route
| Route | Monthly Cost |
|---|---|
| Research peptide vendor | ~$120–$300/month |
| Telehealth / compounded | ~$200–$500/month |
| Concierge medical clinic | ~$445–$1,500/month |
| Brand (Egrifta SV, Rx only) | ~$3,000/month |
Reconstitution & Stability
Tesamorelin is reconstituted with bacteriostatic water, injected subcutaneously in the abdomen only, once daily. Reconstituted with bacteriostatic water and refrigerated, stability data show 14–21 days — shorter than most peptides. This creates a practical vial-size constraint: the 10 mg vial is the largest practical size to use within the stability window. Standard practice is one 10 mg vial reconstituted at a time, used within 10–14 days, with remaining vials kept sealed and refrigerated in powder form. Thepeptidecatalog
Dosing
Most protocols use 2 mg once daily subcutaneously. Egrifta SV uses 1.4 mg daily and Egrifta WR uses 1.28 mg daily. No ramp-up is required — full dose from day one. Peptidedosingprotocols
⚠️ Counterfeiting Warning
Tesamorelin is the peptide most commonly counterfeited — cheaper sermorelin or CJC-1295 is often relabeled as tesamorelin. A mass spectrometry COA showing 5,196 Da is non-negotiable when verifying authenticity. A 3,358 Da reading is sermorelin; a 3,647 Da reading is CJC-1295. Always buy from vendors with independent third-party testing. Thepeptidecatalog
FDA Status
As of June 2026, tesamorelin is FDA-approved only for reduction of excess abdominal fat in HIV-infected adults with lipodystrophy. Use for general visceral fat reduction, metabolic syndrome, or body composition is considered off-label or research use.





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