Bacteriostatic water is sterile water that contains a small amount of benzyl alcohol (typically 0.9%) as a preservative, which inhibits the growth of bacteria without necessarily killing them (hence “bacteriostatic”).
Key Characteristics
Composition: Sterile water + 0.9% benzyl alcohol
Purpose: The preservative allows the vial to be used multiple times over a period of time (usually up to 28 days after opening) without contamination risk.
Common Uses
- Reconstituting medications — dissolving lyophilized (freeze-dried) drugs like peptides, hormones, or antibiotics into solution for injection
- Diluting medications — bringing concentrated drugs to an appropriate dose
- Compounding pharmacies — used as a diluent in preparing injectable formulations
Bacteriostatic Water vs. Sterile Water for Injection
| Feature | Bacteriostatic Water | Sterile Water for Injection |
|---|---|---|
| Preservative | Yes (benzyl alcohol) | No |
| Multi-dose use | Yes (up to 28 days) | Single-use only |
| Vial size | Often 30 mL multi-dose | Smaller, single-dose |
| Newborn use | Not safe | Preferred |
Important Safety Notes
- Not for newborns or infants — benzyl alcohol can be toxic to neonates
- Not for intrathecal use (spinal injections)
- Should only be used when mixed with a compatible drug — not injected alone in large volumes
- Requires a prescription in many countries and should be used under medical supervision







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